• P-ISSN 2277-3525 E-ISSN 2582-7901

Journal of Multidisciplinary
Dental Research

Article

Journal of Multidisciplinary Dental Research

DOI: 10.38138/JMDR/v8i2.22.42

Volume: 8, Issue: 2, Pages: 74-77

Review Article

Pediatric Head and Neck Malignancies

R Sowmya 1 , Sowndarya Gunasekaran​ ✉ 2 , D Vinola 3 , J Baby John 4 , Basil M Mathew 2 , Pradeep Daniel Gainneos 2

1 CRI, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), NH 47 Sankari Main Road, Ariyanoor, Salem, 636308, India
2 Assistant Professor, Department of Pediatric and Preventive Dentistry, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, 636308, India
3 Professor and HOD, Department of Pediatric and Preventive Dentistry, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), NH 47 Sankari Main Road, Ariyanoor, Salem, 636308, India
4 Professor and Dean, Department of Pediatric and Preventive Dentistry, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, 636308, India

Corresponding author ✉: [email protected]

Received Date:19 September 2022, Accepted Date:25 November 2022, Published Date:28 December 2022

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Head and neck masses represents a common clinical entity in pediatric age group. In general, these masses are classified in to developmental, inflammatory, or neoplastic. Having a working knowledge of these lesions in head and neck region & conducting a thorough history & physical examinations generally enable the clinician to simplify an appropriate workup and establish a diagnosis. The differential diagnosis is wide-ranging, and expeditiously distinguishing the benign from malignant masses is difficult for instituting a timely multidisciplinary approach to the management of malignancy. Malignancy of the head and neck account for approximately 5% of all childhood carcinomas. This review aims to discuss the most common head and neck malignancies in childhood. The evidence for the diagnosis and management of childhood, head and neck malignancy is summarized. The rarity of these tumors are inevitably results in a paucity of high-level evidence to guide the treatment.

Keywords: Children, Head and neck malignancy, Lymphoma, Malignancy, Rhabdomyosarcoma

References

  1. Albright JT, Topham AK, Reilly JS. Pediatric head and neck malignancies: US incidence and trends over 2 decades. Archives of Otolaryngology-Head & Neck Surgery. 2002;128(6):655–664. Available from: https://doi.org/10.1001/archotol.128.6.655
  2. Chadha NK, Forte V. Pediatric head and neck malignancies. Current Opinion in Otolaryngology & Head and Neck Surgery. 2009;17(6):471–477. Available from: https://doi.org/10.1097/MOO.0b013e3283323893
  3. Sutow WW. Cancer of the Head and Neck in Children. JAMA. 1964;190(5):414–420.
  4. Jaffe BF, Jaffe NF. Head and neck tumors in children. Pediatrics. 1973;51(4):731–740.
  5. Cunningham MJ, Myers EN, Bluestone CD. Malignant tumors of the head and neck in children a twenty-year review. International Journal of Pediatric Otorhinolaryngology. 1987;13(3):279–292. Available from: https://doi.org/10.1016/0165-5876(87)90109-1
  7. Mauz-Körholz C, Metzger ML, Kelly KM, Schwartz CL, Castellanos ME, Dieckmann K, et al. Pediatric Hodgkin Lymphoma. Journal of Clinical Oncology. 2015;33(27):2975–2985. Available from: https://doi.org/10.1200/jco.2014.59.4853
  8. Hodgson DC, Hudson MM, Constine LS. Pediatric Hodgkin Lymphoma: Maximizing Efficacy and Minimizing Toxicity. Seminars in Radiation Oncology. 2007;17(3):230–242. Available from: https://doi.org/10.1016/j.semradonc.2007.02.009
  9. Sandlund JT. Non-Hodgkin Lymphoma in Children. Current Hematologic Malignancy Reports. 2015;10(3):237–243.
  10. Minard-Colin V, Brugières L, Reiter A, Cairo MS, Gross TG, Woessmann W, et al. Non-Hodgkin Lymphoma in Children and Adolescents: Progress Through Effective Collaboration, Current Knowledge, and Challenges Ahead. Journal of Clinical Oncology. 2015;33(27):2963–2974. Available from: https://doi.org/10.1200/jco.2014.59.5827
  11. Reiter A. Non-Hodgkin Lymphoma in Children and Adolescents. Klinische Pädiatrie. 2013;225(S 01):S87–S93.
  12. Koscielniak E, Morgan M, Treuner J. Soft tissue sarcoma in children. Pediatric Drugs. 2002;4:21–29.
  13. Meyer WH, Spunt SL. Soft tissue sarcomas of childhood. Cancer treatment reviews. 2004;30:269–280.
  14. Sengupta S, Pal R, Saha S, Bera SP, Pal I, Tuli IP. Spectrum of head and neck cancer in children. Journal of Indian Association of Pediatric Surgeons. 2009;14(4):200–203. Available from: https://doi.org/10.4103%2F0971-9261.59601
  15. Möller P, Perrier M. Dento-maxillofacial sequelae in a child treated for a rhabdomyosarcoma in the head and neck: A case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 1998;86:297–303. Available from: https://doi.org/10.1016/s1079-2104(98)90175-5
  16. Hayes-Jordan A, Andrassy R. Rhabdomyosarcoma in children. Current Opinion in Pediatrics. 2009;21(3):373–378. Available from: https://doi.org/10.1097/MOP.0b013e32832b4171
  17. Hicks J, Flaitz C. Rhabdomyosarcoma of the head and neck in children. Oral oncology. 2002;38:450–459. Available from: https://doi.org/10.1016/S1368-8375(01)00105-1
  18. Neto JCdA, Antoneli CBG, Ribeiro KB, Castilho MS, Novaes PERS, Chojniak MMM, et al. Retinoblastoma in children older than 5 years of age. Pediatric Blood & Cancer. 2007;48(3):292–295. Available from: https://doi.org/10.1002/pbc.20931
  19. Shields CL, Shields JA, Shah P. Retinoblastoma in older Children. Ophthalmology. 1991;98(3):395–399. Available from: https://doi.org/10.1016/s0161-6420(91)32283-8
  20. Shields CL, Shields JL, Materin M. Retinoblastoma. In: Ocular Oncology. (pp. 91-99) Jaypee Brothers Medical Publishers (P) Ltd.. 2019.
  21. Dombrowski ND, Wolter NE, Irace AL, Robson CD, Perez-Atayde AR, Mack JW, et al. Squamous cell carcinoma of the head and neck in children. International Journal of Pediatric Otorhinolaryngology. 2019;117:131–137. Available from: https://doi.org/10.1016/j.ijporl.2018.11.019
  22. Pao WJ, Hustu HO, Douglass EC, Beckford NS, Kun LE. Pediatric nasopharyngeal carcinoma: Long term follow-up of 29 patients. International Journal of Radiation Oncology Biology Physics. 1989;17(2):299–305. Available from: https://doi.org/10.1016/0360-3016(89)90443-4
  23. Ayan I, Kaytan E, Ayan N. Childhood nasopharyngeal carcinoma: from biology to treatment. The Lancet Oncology. 2003;4(1):13–21. Available from: https://doi.org/10.1016/s1470-2045(03)00956-2
  24. Luna MA, Batsakis JG, El-Naggar AK. Salivary Gland Tumors in Children. Annals of Otology, Rhinology & Laryngology. 1991;100(10):869–871. Available from: https://doi.org/10.1177/000348949110001016
  25. Castro EB, Huvos AG, Strong EW, Foote FW. Tumors of the major salivary glands in children. Plastic and Reconstructive Surgery. 1972;50(1):312–317.
  27. Thariat J, Vedrine PO, Orbach D, Marcy PY, Badoual C, Butori C, et al. Salivary gland tumors in children. Bulletin du Cancer. 2011;98(7):847–855.

COPYRIGHT

© 2022 Published by International Dental Educationists’ Association (IDEA). This is an open-access article under the CC BY license (https://creativecommons.org/licenses/by/4.0/)

  • 30 December 2022
  • VIEWS 490
  • PDF 155
Article Metrics


More articles

DON'T MISS OUT!

Subscribe now for latest articles, news.