• P-ISSN 2277-3525 E-ISSN 2582-7901

Journal of Multidisciplinary
Dental Research

Article

Journal of Multidisciplinary Dental Research

Volume: 10, Issue: 1, Pages: 12-16

Case Report

Oral Submucous Fibrosis - Case Series

Received Date:10 April 2023, Accepted Date:31 May 2023, Published Date:22 July 2024

Abstract

Oralsubmucous fibrosis is regarded as a collagen metabolic disorder with an overall increased collagen production and decreased collagen degradation resulting in increased collagen deposition in the oral tissues, and fibrosis due to alkaloid exposure. We report three case reports of oral submucous fibrosis. Clinical findings and histopathologic findings were consistent with the diagnosis of stage 2 oral submucous fibrosis. The patient was educated on the effects of areca nut and chances of malignant transformation.

Keywords

Malignant Transformation, Oral Submucous Fibrosis, Pathogenesis, Management

References

  1. Warnakulasuriya S, Tilakaratne WM, Kerr A. Oral submucous fibrosis. (pp. 329-353) Cham. Springer. 2017.
  2. Kalra SK, Lathi AA, Lathi SA. A Comprehensive Review of Etiopathogenesis of Oral Submucous Fibrosis. International Journal of Head and Neck Surgery. 2015;6(2):76–79. Available from: https://www.ijhns.com/doi/IJHNS/pdf/10.5005/jp-journals-10001-1227
  3. Wang YYY, Tail YHH, Wang WCY, Chen CYY, Kao YHH, Chen YKY, et al. Malignant transformation in 5071 southern Taiwanese patients with potentially malignant oral mucosal disorders. BMC Oral Health. 2014;14(1):1–9. Available from: https://doi.org/10.1186/1472-6831-14-99
  4. Khanna JN, Andrade NN. Oral submucous fibrosis: a new concept in surgical management. International Journal of Oral and Maxillofacial Surgery. 1995;24(6):433–439. Available from: https://dx.doi.org/10.1016/s0901-5027(05)80473-4
  5. Merchant AT, Haider SM, Fikree FF. Increased severity of oral submucous fibrosis in young Pakistani men. Br J Oral Maxillofac Surg. 1997;35(4):284–291. Available from: https://doi.org/10.1016/s0266-4356(97)90049-8
  6. Sarode SC, Mahuli A, Sarode GS, Mahuli S. Why only areca nut chewing cannot cause oral submucous fibrosis? . 2013. Available from: https://doi.org/10.1016/j.mehy.2013.02.025
  7. Jiang X, Hu J. Drug Treatment of Oral Submucous Fibrosis: A Review of the Literature. Journal of Oral and Maxillofacial Surgery. 2009;67(7):1510–1515. Available from: https://doi.org/10.1016/j.joms.2008.12.056
  8. Pandya S, Chaudhary AK, Singh M, Singh M, Mehrotra R. Correlation of histopathological diagnosis with habits and clinical findings in oral submucous fibrosis. Head Neck Oncol. 2009;1:2691735. Available from: https://doi.org/10.1186/1758-3284-1-10
  9. Lal D. Diffuse oral submucous fibrosis. J All India Dent Assoc. 1953;26:1–3.
  10. Cox SC, Walker DM. Oral submucous fibrosis. A review. Aust Dent J. 1996;41(5):294–303. Available from: https://pubmed.ncbi.nlm.nih.gov/8961601
  11. Arakeri G, Brennan PA. Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management. British Journal of Oral and Maxillofacial Surgery. 2013;51(7):587–593. Available from: https://doi.org/10.1016/j.bjoms.2012.08.014
  12. Rajalalitha P, Vali S. Molecular pathogenesis of oral submucous fibrosis – a collagen metabolic disorder. Journal of Oral Pathology & Medicine. 2005;34(6):321–328. Available from: https://doi.org/10.1111/j.1600-0714.2005.00325.x
  13. Murti PR, Bhonsle RB, Gupta PC, Daftary DK, Pindborg JJ, Mehta FS. Etiology of oral submucous fibrosis with special reference to the role of areca nut chewing. Journal of Oral Pathology & Medicine. 1995;24(4):145–152. Available from: https://doi.org/10.1111/j.1600-0714.1995.tb01156.x

COPYRIGHT

© 2024 Published by International Dental Educationists’ Association (IDEA). This is an open-access article under the CC BY license (https://creativecommons.org/licenses/by/4.0/) 

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