• P-ISSN 2277-3525 E-ISSN 2582-7901

Journal of Multidisciplinary
Dental Research

Article

Journal of Multidisciplinary Dental Research

DOI: 10.38138/JMDR/v11i1.25.20

Volume: 11, Issue: 1, Pages: 20-23

Case Report

Lipoid Proteinosis Beyond the Skin: Unmasking its Oral Presentation

Abrielle K Lamphere1,∗

1Clinical Assistant Professor, Department of Comprehensive Care and Allied Sciences, School of Dentistry, Indiana University Fort Wayne, Indiana, USA

*Corresponding Author
Email: [email protected]

Received Date:18 April 2025, Accepted Date:13 May 2025, Published Date:23 July 2025

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Lipoid proteinosis (LP) is a rare congenital disorder marked by hyaline material accumulation in various organs, with only about 400 cases reported. Clinical manifestations range from asymptomatic skin lesions to severe laryngeal obstruction, including hoarseness from infancy, mucocutaneous involvement, moniliform blepharosis, and dental anomalies like tooth aplasia. Although no cure exists, symptomatic treatment can manage LP's effects. This case report presents a 28-year-old female with recurrent skin lesions, hoarseness, moniliform blepharosis, and dental anomalies, including seven congenitally missing teeth and limited mouth opening. Early recognition and management of dental complications are critical for maintaining oral health in LP patients. Understanding LP's clinical features is vital for improving patient care and expanding knowledge of congenital disorders.

Keywords: Lipoid proteinosis, Dental, Aplasia, Metabolic

References

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COPYRIGHT

© 2025 Published by International Dental Educationists’ Association (IDEA). This is an open-access article under the CC BY license (https://creativecommons.org/licenses/by/4.0/) 

  • 24 July 2025
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