• P-ISSN 2277-3525 E-ISSN 2582-7901

Journal of Multidisciplinary
Dental Research

Article

Journal of Multidisciplinary Dental Research

DOI: 10.38138/JMDR/v10i2.20

Volume: 10, Issue: 2, Pages: 65-67

Original Article

Reviving Furcation: Hyaluronic Acid and Xenograft for Grade II Defects

A K Aysha Safoora1,∗, Krishnaraj Ganeshnarayanan2, K B Uthappa3, Rashmi S Pattanshetty3

1Postgraduate, Deptartment of Periodontics, Coorg Institute of Dental Sciences, Virajpet, Karnataka, India
2Professor, Dept of periodontics, Coorg Institute of Dental Sciences, Virajpet, Karnataka, India
3Reader, Dept of periodontics, Coorg Institute of Dental Sciences, Virajpet, Karnataka, India

*Corresponding Author
Email: [email protected]

Received Date:30 September 2024, Accepted Date:12 December 2024, Published Date:30 December 2024

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Furcation involvement in periodontal therapy, particularly in molars, is challenging, and conventional treatments often yield suboptimal results. Advances in understanding inflammation have led to exploring extracellular matrix (ECM) components like hyaluronic acid (HA) to enhance healing and regeneration. To assess the effects of HA combined with xenograft in treating a Grade II furcation defect in a patient with chronic periodontitis. A patient with grade II furcation underwent open flap debridement, receiving a xenograft combined with hyaluronic acid (HA). Radiographic and clinical parameters, including probing pocket depth (PPD), furcation involvement, and bleeding on probing (BOP), were measured at baseline, 6 months, and 9 months. Significant improvements were observed in clinical parameters at the 9-month follow-up: PPD and furcation involvement showed a marked reduction, and BOP decreased. Radiographic evidence indicated substantial bone fill within the defect. The combined use of HA and a bone graft in treating Grade II furcation defects led to improved clinical outcomes and radiographic evidence of bone regeneration. This case report supports the potential of HA as an adjunctive treatment in periodontal therapy for furcation involvement.

Keywords: Extracellular matrix, Furcation, Hyaluronic acid, Regeneration, Xenograft

References

  2. Avila-Ortiz G, Buitrago JGD, Reddy MS, MS. Periodontal regeneration - Furcation defects: A systematic review from the AAP Regeneration Workshop. Journal of Periodontology. 2015;86(2 Suppl):S108–S130. Available from: https://doi.org/10.1902/jop.2015.130677
  3. Moseley R, Waddington RJ, Embery G. Hyaluronan and its potential role in periodontal healing. Dent Update. 2002;29(3):144–148. Available from: https://doi.org/10.12968/denu.2002.29.3.144
  4. Bansal J, Kedige SD, Anand S. Hyaluronic acid: A promising mediator for periodontal regeneration. Indian Journal of Dental Research. 2010;21(4):575–578. Available from: https://doi.org/10.4103/0970-9290.74232
  8. Arpağ OF, Damlar I, Altan A, Tatli U, Günay A. To what extent does hyaluronic acid affect healing of xenografts? A histomorphometric study in a rabbit model. Journal of Applied Oral Science. 2018;26:1–8. Available from: https://doi.org/10.1590/1678-7757-2017-0004
  9. Briguglio F, Briguglio E, Briguglio R, Cafiero C, Isola G. Treatment of infrabony periodontal defects using a resorbable biopolymer of hyaluronic acid: A randomized clinical trial. Quintessence International. 2013;44(3):231–240. Available from: https://doi.org/10.3290/j.qi.a29054

COPYRIGHT

© 2024 Published by International Dental Educationists’ Association (IDEA). This is an open-access article under the CC BY license (https://creativecommons.org/licenses/by/4.0/) 

  • 19 January 2025
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